During the Greco Roman Byzantine era (380-1204/1453 CE), the Mediterranean region saw a mix of Greek traditions and new Christian beliefs take root. The emperor Constantine established Constantinople as the center of the empire and Theodosius the Great legalized the Christian religion as the faith of the Roman Empire. During this time, a vibrant fusion of Greek, Roman, and Christian influences emerged, paving the way for an immense cultural development. During the Christian period of the Roman Empire, Byzantium thrived as a hub for artistry and learning, contributing greatly to the preservation by manuscripts of classical knowledge while also encouraging progress in theology and architecture fields. Iconic buildings like the Hagia Sophia showcase the architectural achievements of that era. Even after the conquest of Constantinople in 1453, the empire’s impact endured, leaving a lasting humanistic influence on the Western world.